摘要
目的:探讨轮状病毒肠炎患儿血清锌水平及补锌治疗的意义。方法:检测252例轮状病毒肠炎患儿血清锌水平与正常儿童锌水平进行对照,并将252例轮状病毒肠炎患儿随机分成对照组124例和治疗组128例,两组均常规抗病毒、补液纠酸、对症等综合治疗,治疗组在常规治疗的基础上加用葡萄糖酸锌片。结果:轮状病毒肠炎患儿血清锌浓度水平明显低于本地区同龄健康儿童血清锌浓度水平,两组比较差异有统计学意义(P<0.01);总有效率治疗组87.50%,对照组58.87%,两组比较差异有统计学意义(χ2=25.00,P<0.01)。结论:轮状病毒肠炎患儿血清锌水平较同龄健康儿童低,在常规治疗的基础上补充葡萄糖酸锌可提高疗效。
Objective： To explore the change of serum zinc level of children with rotavirus enteritis and the significance of zinc reinforcement. Methods： Serum zinc level of 252 cases rotavirus enteritis children were determined, and compared with serum zinc level of normal children. Randomly 252 cases of rotavirus enteritis were divided into treatment group （n = 128 ） and control group （n = 124 ）. Two groups were treated with routine therapy, such as anti-virus, fluid infusion, acidosis correction and so on. Treatment group in addition to diarrhea conventional therapy was given zinc gluconate. Results： Compared with normal children, the ones suffering from rotavirus enteritis had lower serum zinc level, there was significant differences （P 〈0.01 ）. The total efficacy of treatment group was 87.5% and control group was 58.87%, there was a significant difference （X^2 =25.00, P 〈0.01 ）. Conclusions： The ones suffering from rotavirus enteritis have lower serum zinc level, in addition to diarrhea conventional therapy, giving zinc gluconate treatment has better effect on enhancing curative effect of rotavirus enteritis.
出处
《儿科药学杂志》
CAS
2010年第1期18-20,共3页
Journal of Pediatric Pharmacy
