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甘露聚糖结合凝集素补体途径与糖尿病肾病发病关系的研究进展 被引量：1

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摘要 糖尿病肾病（Diabetic Nephropathy，DN）是糖尿病重要的晚期并发症，可单独发生在15-40％的所有1型和2型糖尿病患者中。近年来许多证据阐明了甘露聚糖结合凝集素（mannose-binding lectin，MBL）及其补体激活与疾病的重要关系，尤其是与糖尿病以及糖尿病肾病的关系。本文综述了MBL的结构、功能、与各种疾病的联系，以及MBL补体途径激活与糖尿病肾病关系的研究进展。
作者 武晓慧 樊文星 黄颂敏
机构地区 四川大学华西医院肾内科
出处 《西部医学》 2010年第2期340-342,共3页 Medical Journal of West China
关键词 糖尿病肾病 甘露聚糖结合凝集素 结构 功能
分类号 R587.1 [医药卫生—内分泌]
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参考文献37

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共引文献20

同被引文献7

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西部医学
2010年 第2期

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