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吞咽康复训练联合抗抑郁药治疗脑卒中后吞咽障碍的疗效观察 被引量:18

Clinical observation of swallowing rehabilitation effect combined with antidepressant in the treatment of post-stroke dysphagia
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摘要 目的观察吞咽康复训练联合抗抑郁药治疗脑卒中后吞咽障碍的临床疗效。方法脑卒中后并发吞咽障碍133例住院患者随机分为治疗组(68例)和对照组(65例),2组患者均接受神经内科常规治疗,1周内给予吞咽康复训练,治疗组在此基础上给予抗抑郁药帕罗西丁,起始剂量10mg/d,早餐后服用,第2周增加至20mg/d。4周后进行疗效评定。结果治疗组有效率92.65%,对照组有效率76.93%,两组比较差异有统计学意义,χ2=6.64,P<0.05。结论抗抑郁药帕罗西丁能明显提高脑卒中后吞咽障碍的疗效。 Objective To evaluate the effecting of rehabilitation training combined with antidepressant in the treatment of post stroke dysphagia. Methods 133 inpatients of post stroke were divided randomly into the treatment group and the control group. All patients were treated by conventional of neurology therapy and swallowing rehabilitation in one week. The patients of therapy group vere given the antidepressants Paroxetine. The therapeutical dose was 20 mg/d. Clinical evaluation after four weeks. Results The effective rate of the treatment was 92. 65% and the control group was 76. 93%. There was significance of difference between the two groups, x^2 = 6. 64 , P 〈 0. 05. Conclusion Antidepressant Paroxetine can significantly improve the efficacy of dysphagia after stroke.
作者 刘素君 陈娟
出处 《中华脑血管病杂志(电子版)》 2009年第4期14-16,共3页 Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
关键词 脑卒中 吞咽障碍 帕罗西丁 吞咽康复训练 Stroke Dysphagia Paroxetine Swallowing rehabilitation
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