摘要
患者女,26岁。出生后6个月发病,双手、足对称性红斑角化25年。体检:一般情况良好。双侧掌跖及腕关节屈侧对称性分布边界清楚的角化性红斑,边缘覆以少许脱屑,压之不褪色,指/趾甲均未受累。实验室检查未见异常。手背侧缘皮损组织病理示:表皮明显角化过度,伴轻度角化不全,颗粒层及棘层肥厚,表皮增生至同一水平线,真皮小血管轻度扩张充血,管周少量淋巴细胞浸润。诊断:进行性对称性红斑角化症。
A 26-year-old female had presented with erythemas and keratinizations on her hands and feet for 25 years since 6 months old. Physical examinations showed that the patient was healthy in general, with symmetry erythemas and keratinizations on her hands, feet and the flexor aspect of wrist joints. The lesions had clear boundaries and few scales on the edge, without destainess after pression. Nails were not involved. Laboratory examinations were normal. Histopathology showed marked hyperkeratosis, parakeratosis and perivascular infiltrate mainly by lymphocyte in the papillary dermis. Diagnosis： Progressive symmetric erythrokeratodermia （PSEK）.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2010年第1期73-74,共2页
The Chinese Journal of Dermatovenereology
关键词
进行性对称性红斑角化症
Progressive symmetric erythrokeratodermia
