摘要
肝脏是结直肠癌最常见的远处侵犯器官。手术切除仍是目前唯一有治愈希望的治疗手段。术后患者可以获得25%-39%的5年生存率。但仅有10%-25%的患者确诊时适合手术切除。新疗法如消融术、肝动脉介入化疗、新辅助化疗、靶向治疗等,给不宜手术的患者带来了希望。本文以外科治疗为主对结直肠癌肝转移的治疗做简要综述。
The liver is a primary target organ of colorectal cancer metastases. Surgical resection is presently the only approach that offers patients a substantial chance of cure. Five-year survival ranges 25% -39%. But by the time of diagnosis, only 10%-25% of patients were considered eligible for surgical directed thera- pies. New therapeutic modalities such as ablation, hepatic arterial infusion chemotherapy,neoadjuvant chem- otherapy and targeted therapy present promise for the future treatment of unresectable liver metastases. These treatments and progress in surgical therapy are reviewed in this article.
出处
《国际外科学杂志》
2010年第2期105-108,共4页
International Journal of Surgery
基金
上海自然(青年)科学基金(No.04ZR14006)
关键词
结直肠癌
肝转移
手术治疗
新辅助化疗
Colorectal cancer
Liver metastasis
Liver metastasectomy
Neoadjuvant chemotherapy