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结直肠癌肝转移的外科治疗现状与进展 被引量:5

Current therapeutic options and progress for colorectal liver metastases
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摘要 肝脏是结直肠癌最常见的远处侵犯器官。手术切除仍是目前唯一有治愈希望的治疗手段。术后患者可以获得25%-39%的5年生存率。但仅有10%-25%的患者确诊时适合手术切除。新疗法如消融术、肝动脉介入化疗、新辅助化疗、靶向治疗等,给不宜手术的患者带来了希望。本文以外科治疗为主对结直肠癌肝转移的治疗做简要综述。 The liver is a primary target organ of colorectal cancer metastases. Surgical resection is presently the only approach that offers patients a substantial chance of cure. Five-year survival ranges 25% -39%. But by the time of diagnosis, only 10%-25% of patients were considered eligible for surgical directed thera- pies. New therapeutic modalities such as ablation, hepatic arterial infusion chemotherapy,neoadjuvant chem- otherapy and targeted therapy present promise for the future treatment of unresectable liver metastases. These treatments and progress in surgical therapy are reviewed in this article.
出处 《国际外科学杂志》 2010年第2期105-108,共4页 International Journal of Surgery
基金 上海自然(青年)科学基金(No.04ZR14006)
关键词 结直肠癌 肝转移 手术治疗 新辅助化疗 Colorectal cancer Liver metastasis Liver metastasectomy Neoadjuvant chemotherapy
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