摘要
同步观察１０只家兔肝缺血再灌注损伤（ＨＩＲＩ）时血脂质过氧化物的浓度、谷丙转氨酶活性及肝形态学的变化。发现脂质过氧化物浓度升高与谷丙转氨酶活性增高呈高度显著正相关（ｒ＝０．７３３，Ｐ＜０．０１），并与肝损伤的严重程度呈平行关系。表明脂质过氧化反应在ＨＩＲＩ的发生。
he variation of lipid peroxide (LPO) concentration, glutamate pyruvate transaminase (GPT) activity in the plasma and the morphological changes of liver were observed synchronously during hepatic ischemiareperfusion injury (HIRI) in 10 rabbits. It was found that LPO content increased progressively while GPT activity rose almost in a straight line and there were the positive relationship very significantly (r=0. 733, P<0.01 ) between LPO and GPT, and LPO content was in parallel relationship with the degree of hepatocellular damage.It indicated that LPO would play an important role in the happening and developing of HIRI.
出处
《中国应用生理学杂志》
CAS
CSCD
1998年第3期214-216,共3页
Chinese Journal of Applied Physiology
基金
浙江省教委科研基金
