摘要
目的观察和评价胸腔内注入尿激酶治疗结核性胸膜炎的疗效。方法将确诊的结核性膜炎患者40例，随机均分为尿激酶治疗组和对照组，在常规应用抗结核药物和胸穿抽液的基础上，尿激酶治疗组于每次抽液后用注人生理盐水20ml稀释尿激酶10万u，对照组在胸穿抽液后注入生理盐水20ml，两组抗结核化疗方案相同。结果治疗组在抽液量、胸膜厚度、胸膜粘连度与对照组有显著性差异（P〈0．05）。结论胸腔内注入尿激酶治疗结核性胸膜炎可以增加抽胸液量，减轻胸膜肥厚、粘连，改善肺功能。
Objective To investigate the effects of intrapleural injection of urokinase in treatment of tuberculous pleurisy. Methods The 40 cases with tuberculous pleural effusion were randomly divided into treatment group and control group. The cases in treatment group were treated with 100 000 IU urokinase（ diluted by 20 ml normal saline）after draining effusion and those in the control group were only given normal saline after draining of effusion. Results The effects in treatment group was significantly superior to those of the control group （ P 〈 0. 05）. Conclusion Intrapleural urokinase is effective for treatment of patients with tuberculous pleurisy.
出处
《中国临床实用医学》
2010年第1期38-39,共2页
China Clinical Practical Medicine
关键词
尿激酶
胸膜炎
结核
Urokinase
Pleural effusion
Tuberculous pleurisy
