HNL和PCT检测对儿童急性细菌性呼吸道感染的诊断价值被引量：3

Value of detection of HNL and PCT diagnosis of acute bacterial respiratory tract infections in children

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摘要目的评价中性粒细胞脂钙素(HNL)和降钙素原(PCT)的检测对儿童急性细菌性呼吸道感染的诊断价值。方法76例5d^14岁伴有急性呼吸道感染(ARI)症状的儿童患者,检测血清HNL和PCT含量,并与ARI常规诊断指标CRP、WBC和ESR进行比较,运用受试者工作特性曲线(ROC)评价上述各指标对诊断儿童细菌性ARI的价值。结果细菌感染组HNL、PCT、CRP、WBC和ESR显著高于病毒感染组(P<0.01),上述各指标的AUC分别为0.903(95%CI:0.813～0.959),0.987(95%CI:0.930～0.998),0.962(95%CI:0.891～0.992),0.839(95%CI:0.736～0.921)以及0.891(95%CI:0.798～0.951)。结论HNL和PCT对儿童ASI的诊断价值与CRP相当,但优于WBC、ESR。 Objective To assess the value of detection of neutrophil lipocalin （HNL） and procalcitonin （PCT） in diagnosis of acute bacterial respiratory tract infection in children. Methods The levels of HNL,PCT,CRP,WBC and ESR in 76 children aged from 5 days to 14 years,admitted due to acute respiratory tract infection （ARI）.were determined . Results There levels of HNL,PCT,CRP,WBC,and ESR were significantly higher in group with bacterial infection than those with viral infection （P〈0.01）. The area under the ROC （AUC） obtained was 0.903 （95% CI： 0.813-0.959） for HNL, 0.987 （95% CI： 0.930 -0.998） for HCT,0.962 （95% CI： 0.8914）.992） for CRP,0.839 （95% CI： 0.736 -4）.921） for WBC, and 0.891 （95% CI： 0.798- 0.951） for ESR. Conclusion HNL and PCT are valuable than WBC and ESR for diagnosing of ASI in children.

作者胡宏波詹前美刘和艳

机构地区柳州市柳铁中心医院检验科

出处《中国热带医学》 CAS 2010年第2期223-224,253,共3页 China Tropical Medicine

关键词中性粒细胞脂钙素降钙素原急性呼吸道感染儿童 Neutrophil lipocabn Procalcitonin Acute respiratory tract infection

分类号 R725.6 [医药卫生—儿科]

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