摘要
目的:建立沉香化滞丸的质量标准。方法:采用薄层色谱(TLC)法对制剂中的木香、香附、山楂、大黄、厚朴、牵牛子进行定性鉴别;采用高效液相色谱法测定制剂中橙皮苷的含量。结果:TLC显色清晰且阴性对照无干扰。橙皮苷的检测浓度在0.0242～0.4832mg·mL-1范围内与峰面积积分值呈良好的线性关系(r=0.9994);平均回收率为102.5%,RSD=2.0%(n=6)。结论:所建标准可用于沉香化滞丸的质量控制。
OBJECTIVE：To develop a method for quality control of Chenxiang huazhi pills. METHODS ：Auklandia lappa, Cyperus rotundus, Crataegus pinnati fida, Rheum palmatum, Magnoliae officinalis and Pharbitis nil were identified by TLC. HPLC was used for determination of hesperidin. RESULTS： The chromatographic spots were identified without interference of negative con- trol. Hesperidin had a good linearity within the range of 0.024 240.483 2 mg-mL ;（r=0.999 4）with average recovery of 102.5% （RSD=2.0% ,n=6）. CONCLUSION： This standard is used for quality control of Chenxiang huazhi pills.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第7期632-634,共3页
China Pharmacy
