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探讨免疫性血小板减少性紫癜血小板计数与骨髓巨核细胞的关系 被引量:1

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摘要 目的:探讨免疫性血小板减少性紫癜(ITP)血小板计数与骨髓巨核细胞数及分类关系。方法:对145例ITP患者根据外周血血小板计数进行分组:Ⅰ组53例(血小板计数〈20×10^9/L),Ⅱ组49例(血小板计数20×10^9/L),Ⅲ组43例(血小板数50-80×10^9/L),各组患者分别行骨髓穿刺、涂片、染色后,用光学显微镜计数全片巨核细胞数,再根据巨核细胞形态特点进行分类,每例患者分50个巨核细胞。结果:Ⅰ、Ⅱ、Ⅲ组巨核细胞总数与对照组比较差异有显著性(P〈0.01);巨核细胞分类中,除原始型巨核细胞Ⅱ、Ⅲ组相比无统计学意义(P〉0.05)外,幼稚、颗粒、产血小板及裸核型巨核细胞三组之间两两相比较差异均有显著性(P〈0.01)。结论:在ITP时,外周血血小板数与骨髓中巨核细胞成熟情况有密切联系,骨髓中产板型巨核细胞越多,外周血小板计数就越多。
出处 《临床医药实践》 2010年第2期129-131,共3页 Proceeding of Clinical Medicine
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