摘要
目的研究冠心病(CHD)患者血清尿酸(UA)与胆红素(BIL)和血浆纤维蛋白原(Fib)水平的变化,探讨其与冠心病(CHD)发生的关系。方法符合条件并经冠脉造影确诊的112例冠心病(CHD)患者为冠心病组,正常健康体检者150例为对照组,空腹抽血检测两组的血清UA与TBIL、DBIL及血浆Fib浓度,应用公式计算出IBIL浓度,并进行相关统计学分析。结果CHD组UA较对照组增高,差异有显著性(P<0.01);Fib与对照组相比较差异有显著性(P<0.05);TBIL、IBIL浓度较对照组明显降低,差异有显著性(P<0.01),DBIL变化不明显。结论血清尿酸(UA)与胆红素(BIL)和血浆纤维蛋白原(Fib)同冠心病(CHD)的发生发展关系密切,是导致CHD的危险因素。
Objective To observe the levels of uric acid（UA）, bilirubin （BIL） and fibrinogen（Fib） to explore the relationships between them in patients with coronary heart disease（CHD）. Methods The levels of UA, BIL and Fib among 112 patients with CHD and 150 normal persons were measured. Results The level of UA in patients with CHD is higher than the control group. The difference is significant （P 〈 0.01 ）. The level of Fib between CHD patients and normal persons is signiiicant （P 〈 0.05）. The concentrations of TBIL and IBIL are lower than the control group （P 〈 0.01）. No significant change was detected on DBIL. Conclusion UA, BIL and Fib participate in the occurrence and development of CHD and they are the risk factors of CHD.
出处
《中国实验诊断学》
北大核心
2010年第2期225-226,共2页
Chinese Journal of Laboratory Diagnosis
关键词
冠心病
尿酸
胆红素
纤维蛋白原
coronary heart disease
uric acid
bilirubin
fibrinogen
