摘要
目的:了解急性高血压性脑出血(AHE)患者血浆胃泌素(Gas)水平的变化,并探讨其临床意义。方法:用放射免疫法对40例AHE患者进行血浆Gas测定,30例正常体检者做对照。结果:AHE患者血浆Gas含量显著高于对照组(P<0.05);在大量出血组、破入脑室组、重度组中的血浆Gas含量分别显著高于中小量出血组(P<0.01)、未破入脑室组(P<0.01)以及中度组(P<0.05);预后差组显著高于预后好组(P<0.05)。结论:血浆Gas参与了脑出血的病理生理过程,可能是重症脑出血导致上消化道出血的原因之一,并与出血量、有无破入脑室、病情甚至预后关系密切。血浆Gas浓度的检测在判断AHE病情及预后方面具有重要作用。
Objective： To investigate the changes of plasma Gastrin（Gas） level in the patients with acute hypertensive encephalorrhagia（AHE） and its clinical significance.Methods： Plasma Gas level of 40 patients with AHE was measured by radioimmunoassay.A total of 30 healthy people on medical examination were used as control.Results： The Gas concentration of the AHE group was significantly higher than that of the control（P﹤0.05）.The patients with massive hemorrhage,bleeding into ventricle,or in severe state had significantly higher Gas level than those with small amount of hemorrhage,no bleeding into ventricle or in moderate state（P0.05）.The Gas concentration of the patients with bad prognosis was significantly higher than that of the patients with good prognosis（P﹤0.05）.Conclusion： Plasma Gas participates in pathophysiological processes of AHE.It may be one of the causes leading to hemorrhage of the upper digestive tract in the patients with AHE,and are related to the amount of hemorrhage,patient＇s condition and prognosis.It is suggested that the measurement of plasma Gas concentration may play an important role in assessing the condition of AHE.
出处
《西北国防医学杂志》
CAS
2010年第1期28-30,共3页
Medical Journal of National Defending Forces in Northwest China
关键词
高血压性脑出血
胃泌素
消化道出血
急性
Hypertensive encephalorrhagia Gastrin Gastrointestinal bleeding Acute
