摘要
目的应用二维超声斑点追踪成像技术(2D-STI)评价肝硬化患者左心室局部纵向收缩功能。方法选取34例肝硬化患者为肝硬化组,35名健康志愿者作为正常对照组。常规超声心动图记录左心房及左心室舒张末期前后径、射血分数(EF)、左室短轴缩短率(FS);心尖长轴切面记录二尖瓣舒张期血流频谱E峰及A峰值,并计算E/A值;记录心尖长轴切面、心尖两腔切面及心尖四腔切面的三个完整心动周期的高帧频二维图像,脱机应用二维应变分析软件测量左心室壁各节段收缩期的峰值应变。结果肝硬化组左心房收缩期前后径(30.49mm±4.20mm)、左心室舒张末期前后径(44.90mm±4.33mm)与正常对照组(28.82mm±3.67mm,43.25mm±3.21mm)比较差异无统计学意义(P>0.05)。肝硬化组EF(61.15%±4.41%)及FS(32.92%±3.34%)与正常对照组(59.74%±5.45%,32.05%±3.71%)比较差异无统计学意义(P>0.05)。肝硬化组E/A值(1.03±0.29)较正常对照组(1.31±2.74)减低,差异有统计学意义(P<0.05)。肝硬化组左心室各节段收缩期纵向峰值应变均低于正常对照组,除左心室后壁基底段、前壁基底段、下壁基底段、前间隔基底段及后间隔中间段和基底段外,其他各节段间差异均有统计学意义(P<0.05)。结论肝硬化患者左心室形态、舒张功能及左心室局部纵向收缩功能均存在异常,2D-STI较常规超声检查可以较早地、敏感地反映肝硬化患者左心室局部纵向收缩功能改变。
Objective To assess the left ventricular longitudinal shrinkage function in liver cirrhosis patierits with two-di mensional speckle tracking imaging （2D-STI）. Methods Echocardiography and Doppler echocardiography were performed in 34 patients with liver cirrhosis and 35 healthy subjects of corresponding ages. High frame rate two dimensional images were recorded from apical long-axis view, four-chamber view and two chamber view of left ventricle; then the left ventricular diameter, left atrium diameter, the peak filling velocity of E wave and A wave, E/A ratio, EF and FS were measured. The peak systolic strain of left ventricular segment was measured with two-dimensional strain software. Results Compared with healthy subjects, left ventrieular diameter, left atrium diameter, EF and FS of liver cirrhosis patients were not statistically different （P〉0.05）, but the E/A ratio was lower （P〈0.05）. The peak systolic strain of most left ventricular segment in liver cirrhosis reduced significantly （P〈0.05）, except that of base segment of posterior wall, anterior wall, inferior wall, anterior and posterior interventricular septum, as well as middle segment of posterior interventricular septum. Conclusion The heart shape, systolic and diastole function of liver cirrhosis are abnormal. 2D-STI can early and accurately evaluate the systolic function of liver cirrhosis.
出处
《中国医学影像技术》
CSCD
北大核心
2010年第2期288-290,共3页
Chinese Journal of Medical Imaging Technology
关键词
超声心动描记术
肝硬化
心室功能
左
Echocardiography
Liver cirrhosis
Ventricular function, left
