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^(125)I植入治疗源的剂量学参数的Monte Carlo模拟 被引量:2

Monte Carlo simulation of dosimetric parameters for the Model 6711 ^(125)I brachytherapy source
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摘要 γ放射性粒子源125I已被广泛用于前列腺和眼睛的植入治疗中。本文采用EGS5蒙特卡罗代码计算了美国医用物理学协会(AAPM)TG-43U1报告中推荐的型号为6711125I近距治疗源(活性区长取0.28cm)的剂量学参数,如剂量率常数、径向剂量函数和各向异性函数。剂量率常数为0.959cGy/h/U,与TG-43U1推荐值和Dolan等已发表的值相差在2.0%以内;径向剂量函数数值与二者均符合较好;随着角度和距离的增加,各向异性函数值数值与二者的复合程度趋佳。并给出了实用性较强的径向剂量函数的拟合公式。 The γ-radioactive seed brachytherapy source has been widely employed in the implantation therapy for the prostatic carcinoma and the ophthalmic, lesions, tn this study the dosimetric parameters for characterization of a low-energy interstitial brachytherapy source ^125I were calculated according to dose calculation formalism recommended by AAPM TG-43UI. For data processing, a 0.28 cm active length was used for the geometry function. The dosimetry parameter air-Kerma strength, dose rate constant, radial dose function and anisotropy function were estimated by means of the EGS5 Monte Carlo code. The results obtained from this study are in good agreement with the corresponding values recommended by TG-43U1 and with the data reported by Dolan, et al.
出处 《介入放射学杂志》 CSCD 北大核心 2010年第1期38-41,共4页 Journal of Interventional Radiology
关键词 近距治疗 I-125 剂量学参数 蒙特卡罗方法 brachytherapy, iodine-125, dosimetric parameter, Monte Carlo method
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