摘要
目的:探讨射频消融治疗晚期肺癌的临床疗效及安全性。方法:对30例晚期肺癌病人,进行射频消融治疗。18例通过CT定位在局麻下经皮穿刺进行,12例在胸腔镜直视下进行。消融温度(70—90)℃,治疗时间(15~90)min。术后4周通过CT扫描评价疗效,观察手术中、后期并发症。结果:30例病人行射频消融术后,手术后4周肿瘤大小无明显缩小,但癌组织密度均有显著降低,表现为凝固性坏死和去血管征象;并发症包括局限性气胸3例,术后少量咯血2例,术后发热16例,胸部灼热痛5例。结论:射频消融术治疗晚期肺癌,损伤小,安全,病人易于接受,治疗有效,远期效果需进一步观察。
Objective:To evaluate the clinical efficacy and safety of radiofrequency ablation in the treatment of advanced lung cancer. Methods:30 patients with advanced lung cancer were treated with radiofrequency catheter ablation. 18 cases of percutaneous CT positioning in the local anesthesia, and 12 cases in the open under thoracoscopic. The melting temperature was (70- 90) ℃, and treatment time ( 15-90) min. To observethe intraoperative complications; the efficacy after the adoption with CT scan evaluation and late complications were investigated after fillow - up for four weeks. Results: the tumor size of 30 patients after radiofrequency ablation had no significant narrowing four weeks after surgery, but the density of tumor tissues were significantly lower, performance to coagulative necrosis and no signs of vascular; Complications included 3 cases of the limitations of pneumothorax ,2 cases of a small amount of hemoptysis, 16 cases of postoperative fever, chest pain in five cases of heartburn. Conclusions: Radiofrequency ablation in the treatment of advanced lung cancer was effective,low - trauma, safe, easy accepted by patients, the long -term effects need further observation.
出处
《青海医药杂志》
2010年第1期1-2,共2页
Qinghai Medical Journal
关键词
射频消融
晚期肺癌
临床疗效
radiofrequency ablation
advanced lung cancer
clinical efficacy