摘要
目的为了了解乙型肝炎(乙肝)的不同传染途径及易感人群的状况。方法2007年1月起至2008年6月对在北京市海淀区妇幼保健院乙肝母婴阻断门诊就诊的乙肝病毒携带者孕妇352例进行了检出乙肝病毒阳性前乙肝接触史调查。结果在352例乙肝病毒携带孕妇中,母亲乙肝病毒阳性93例,占26.42%。与父亲乙肝病毒阳性43例,占12.21%,经统计学处理,χ2=22.78,P=0.000,差异非常显著。父母均乙肝阳性7例占1.99%。孕妇的父母乙肝病毒阳性143例,阳性率占40.6%,与除父母外其他家庭成员乙肝病毒阳性23例(占6.53%)比较经统计学处理,χ2=7.879,P=0.005,差异非常显著。丈夫乙肝病毒阳性45例,占12.78%。同事或同学乙肝病毒阳性7例,占1.98%。曾为受血者3例,占0.85%。曾有补牙和修脚史3例,占0.85%。接种血源性乙肝疫苗后阳性1例,0.28%。未找出任何乙肝接触127例,占36.07%。所有孕妇均否认毒品接触史。总计家庭乙肝感染率211例,占59.94%,与非家庭因素感染141例,占40.06%比较经统计学处理,χ2=27.841,P=0.000,差异非常显著。结论应加强对乙肝家庭乙肝病毒传播的阻断,加强对家庭中有乙肝病毒携带者乙肝疫苗接种。无明确乙型肝炎密切接触史者在乙肝病毒携带者中所占的高比率提醒我们应走出乙型肝炎只能通过血源性传染的误区,重视对一般人群的乙肝免疫。
Objective： To investigating the infectious way and susceptibility person of the hepatitis B. Methods： The hepatitis B contact history before infected of 352 with the hepatitis B virus carrier pregnant woman were investigated, they were examined at department of interrupting the hepatitis B virus from the mother to the infant transmission of Beijing Haidian Gynecology Infantile Health Hospital during from January 2007 to June 2008. Results： In the hepatitis B virus carrier pregnant woman 352 before infected there were 93 whose mother who was the hepatitis B virus carrier （26.42%） ; there were 43 whose father who was the hepatitis B virus carder （ 12. 21% ）, the mother carrier was very marked more than the father carrier （X^2 = 22.78, P = 0. 000） ; there were 7 whose mother and father all were the hepatitis B virus carrier （ 1.99% ） ; there were 45 whose husband was the hepatitis B virus carrier （ 12.78% ） ; there were 23 whose other family member was the hepatitis B virus carrier （6. 53% ） ; there were 7 whose colleague or schoolmate was the hepatitis B virus carrier （ 1.98% ） ; there were 3 who had been transfused blood （0. 85% ） ; there were 3 who had been tooth operated or pedicure history （0. 85% ） ; there was 1 who had inoculated the hepatitis B vaccine of the blood source （0. 28% ） ; there were 127 who deny any the hepatitis B contact history （36. 07% ）. Family the hepatitis B contacted factor21 lcases, （59. 94% ） was very marked more than No - Family the hepatitis B contacted factor 141 cases （40. 06% ）, X^2 = 27. 841, P = 0. 000o All deny to related with opium. Conclusion： It should be strengthen to interrupting family infection the hepatitis B virus through regularly inoculating the hepatitis B vaccine. The high percentage of them without the hepatitis B contact determinate history awake us keep away mistake that the hepatitis B virus infect only through blood, it should be strengthen the hepatitis B virus immunity of the common persons.
出处
《中国优生与遗传杂志》
2010年第1期65-66,共2页
Chinese Journal of Birth Health & Heredity
基金
北京市卫生局妇幼科研基金资助项目(C03011403)
关键词
乙型肝炎
病毒携带者
感染前
接触史
家庭
Hepatitis B virus carrier
Pregnant woman
Contact history
Before infected
Family
