摘要
观察４６例肿瘤病人，分放疗加胸腺肽用药组和单纯放疗组（对照组）。用药组每日静点胸腺肽１６０ｍｇ，连续１０ｄ后用流式细胞仪检测外周血Ｔ细胞亚群的变化。结果表明，用药组放疗后ＣＤ４／ＣＤ８比值、ＣＤ４、ＣＤ２５（ＩＬ－２Ｒ）和ＣＤ５６（ＮＫ）阳性百分率均明显高于本组放疗前及单纯放疗组放疗后水平。提示，大剂量胸腺肽可在短期内提高肿瘤放疗病人机体的免疫功能。
We observed 46 patients with tumor who were divided into radiotherapy plus thymopeptide(TP) and simple radiotherapy(control).The patients in TP were given thymopeptides,160 mg/d,iv,for 10 days.The results showed that CD4/CD8 radio and positive percentages of CD4,CD25 and CD56 after radiotherapy in TP were significantly higher than those before radiotherapy in TP and those after radiotherapy in control.These results suggest that large dose thymopeptides could increase immune function of patients with tumor.
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
1998年第6期438-439,共2页
Chinese Journal of Immunology
关键词
胸腺肽
T细胞亚群
肿瘤
放射疗法
Thymopeptides T cell subpopulations Tumors radiotherapy
