摘要
目的:评价氟伏沙明治疗抑郁症的临床疗效和不良反应。方法:将符合CCMD-3诊断标准的抑郁症患者50例分两组分别给予氟伏沙明片和氯丙咪嗪片治疗,疗程均为56 d。采用汉密尔顿抑郁量表(HAMD)和不良反应量表(TESS)评定疗效和药物不良反应,实验室检查包括血常规、尿常规、血生化和心电图。结果:经过8周治疗,氟伏沙明组与氯丙咪嗪组疗效相近(P>0.05),氟伏沙明组与氯丙咪嗪组的显效率差异无统计学意义(χ2=0.089,P>0.05)。氟伏沙明组不良反应发生率明显少于氯丙咪嗪组。结论:氟伏沙明能有效治疗抑郁症,不良反应轻。
Objective：Clinical efficacy and adverse reaction evaluation of fluvoxamine in treatment depression.Method：50 patients met the criterion of CCMD-3 for depression were assigned randomly to study group or control group treatment for 56 days.The efficacy was assessed by Hamilton Depression Scale（HAMD） and the adverse effects were assessed by Treatment Emergent Symptoms Scale（TESS）.Laboratory tests included blood cell analysis,urinalysis,blood biochemical analysis and electrocardiogram.Result：The two groups clinical efficacy is similar treated 8 weeks,adverse reaction of fluvoxamine group less than clomipramine.Conclusion： Fluvoxamine is rather effective and lesser adverse reaction in treatment of depression.
出处
《内蒙古医学杂志》
2010年第1期32-33,共2页
Inner Mongolia Medical Journal
