3Yuan W, Wu F, Guo MY, et al. Development of protein delivery mierosphere system by a novel S/O/O/W multi-emulsion[J]. European Journal of Pharmaceutical Sciences ,2009,36:216-218.
4He P,Stanley S, Illum L. Chitosan microspheres prepared by spray drying[J].International Journal of Pharmaceutics , 1999,187:53-65.
6Raman C, Berkland C, Kim K, et al. Modeling small-molecule release from PLG rnicrosphere:effect of polymer degradation and nonuniform drug distribution[J].J Controlled Release ,2005,103 ( 1 ) : 149-158.
8Sunit KS,Abdul AM, Prakash CS, et al. Formulation and in vitro evaluation of Eudragit microspheres of Stavudine[ J ]. Tropical Journal of Pharmaceutical Research ,2005,4 ( 1 ) :369-375.
9Fu XD, Ping QN, Gao YL. Effects of formulation factors on encapsulation efficiency and release behaviourin vitroof huperzineh PLGA micmspheres [ J ]. J Microencapsul,2005,22( 1 ) :57-66.
10Geze A, Venier-Julienne M C, Mathieu D, et al. Development of 5-iodo-2-de- oxyuridine milling process to reduce initial burst release from PLGA microparticles [ J ]. International Journal of Pharmacentics, 1999,178 (2) :257 -268.
4Wang J, Wang B M ,Schwendeman S P. Characterization of the initial burst release of a model peptide from poly(d, I-lactide-co-glycolide)microspheres[J].J Control Release 2002,82(2-3):289-307
5Takenaga M, Yamaguchi Y, Kitagawa A, et al. A novel sustained-release formulation of insulin with dramatic reduction in initial rapid release[J]. J Control Release,2002,79(1-3):81-91.
6Boury F, Marchais H, Proust J E,et al. Bovine serum albumin release from poly (α-hydroxy acid) microspheres: effects of polymer molecular weight and surface properties[J]. J Control Release, 1997,45(1) :75-86.
7Bittner B ,Morlock M ,Koll H ,et al. Recombinant human erythropoietin(rhEPO) loaded poly(lactide-co-glycolide) microspheres: influence of the encapsulation technique and polymer purity on microsphere characteristics[J]. Eur J Pharm Biopharm, 1998,45(3):295-305.
8Kim H K,Park T O. Microencapsulation of Human Growth Hormone within biodegradable polyester microspheres: protein aggregation stability and incomplete release mechanism[J].Biotechnol Bioeng, 1999,65(6):660-667.
9Jiang G, Woo B H, Kang F, et al. Assessment of protein release kinetics, stability and protein polymer interaction of lysozyme encapsulated poly (d, 1-Lactice-co-glycolide) microsphercs[J]. J Coatrol Release,2002,79(1-3):137-145
10Sandor M, Enscore D, Weston P, et al. Effect of protein molecular weight on release from micron-sized PLGA microspheres[J].J Control Release,2001,76(3):297-311
