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支气管肺泡灌洗液中CYFRA21-1检测对肺癌的诊断价值

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摘要 目的探讨支气管肺泡灌洗液(BALF)中可溶性细胞角蛋白19片段(CYFRA21-1)检测对肺癌的诊断价值。方法肺癌组45例,对照组20例。采用免疫放射法(IRMA)检测两组BALF和血清中CYFRA21-1水平。结果肺癌组BALF中CYFRA21-1水平高于对照组,且阳性率高于同组血清;鳞癌组BALF中CYFRA21-1水平、阳性率高于腺癌,且阳性率高于同组血清;Ⅰ、Ⅱ期NSCLC患者BALF中CYFRA21-1阳性率高于血清(P<0.05)。结论BALF中CYFRA21-1检测较血清更有助于肺癌尤其是早期肺癌的诊断,且对肺鳞癌诊断价值较高。
出处 《山东医药》 CAS 北大核心 2010年第8期101-103,共3页 Shandong Medical Journal
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