期刊文献+

美托洛尔治疗CHF的临床观察

下载PDF
导出
摘要 慢性充血性心力衰竭(CHF)是以肾素一血管紧张素、交感神经系统过度激活,心室功能恶化和心室重塑为特征的临床综合征。以往慢性心力衰竭的主要治疗药物为洋地黄类和利尿剂。虽然这两类药物可改善患者的临床症状和生活质量,但不能降低患者的总病死率。近20年来,对于CHF的治疗概念有了根本性的转变,即从短期的、血流动力学/药理学措施转变为长期的、修复性策略,目的是改变衰竭心脏的生物学性质。
作者 李小晶
出处 《浙江临床医学》 2010年第3期287-288,共2页 Zhejiang Clinical Medical Journal
  • 相关文献

参考文献6

二级参考文献14

  • 1Beckman JA,Creager MA,Libby P.Diabetes and artherosclerosis:epidemiology,pathophysiology,and management[J].JAMA,2002,287(19):2570-2581.
  • 2Matthews DR,Hosker JP,Rudenski AS,et al.Homeostasis model assessment:insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man[J].Diabetalogia,1985,28(7):412-419.
  • 3Australia-New Zealand Heart Failure Resarch Collaborative Group.Effects of carvedilol,a vasodilator-β-blocker,in patients with congestive heart failure due to ischemic heart disease[J].Circulation,1995,92(2):213-218.
  • 4Kurz T,Richard D,Gorge B,et al.Differential effects of carvedilol on norepinephrine release in normal and ischemic heart[J].J Cardiovasc Pharmacol,2000,36(1):96-100.
  • 5Cargnoni A,Ceconi C,Bernocchi P,et al.Reduction of oxidative stress by carvedilol:role in maintenance of ischemic myocardium viability[J].Cardiovasc Res,2000,47(3):556-566.
  • 6Jacob s,Balletshofer B,Henriksen E J,et al.Beta-blocking agents in patients with insulin resistance:effects of vasodilating beta-blockers[J].Blood Press,1999,8(5-6):261-268.
  • 7Bakris GL,Fonseca V,Katholi RE,et al.Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension:a randomized controlled trial[J].JAMA,2004,292(18):2227-2236.
  • 8Krum H,Roecker EB,Mohacsi P,et al.Effects of initiating Carvedilol in patients with severe chronic heart failure:results from the COPERNICUS study[J].JAMA,2003,289(6):712-718.
  • 9Jonas M,Reicher-Reiss H,Boyko V,et al.Usefulness of beta-blocker therapy in patients with non-insulin-dependent diabetes mellitus and coronary artery disease.Bezafibrate Infarction Prevention (BIP) Study Group[J].Am J Cardiol,1996,77(15):1273-1277.
  • 10Noguchi N,Nishino K,Niki E.Antioxidant action of the antihypertensive drug,carvedilol,against lipid peroxidation[J].Biochem Pharmacol,2000,59(9):1069-1076.

共引文献2447

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部