摘要
为了快捷简便地测定盐酸沙拉沙星可溶性粉生产过程中沙拉沙星的含量,采用紫外分光光度法测定沙拉沙星的含量。结果表明,沙拉沙星对照品质量浓度在2.4μg/mL～12.0μg/mL范围内与吸收度呈良好的线性关系,线性回归方程A=0.088C+0.09,r=0.9999(n=5),平均回收率为99.74%,RSD=0.47%(n=5),与高效液相色谱法比较结果一致。
In order to control the sarafloxacin content in soluble powder in process easily and quickly,UV spectrophotometry was developed referring to the analysis methods of other quinolone preparations.The calibration curve for sarafloxacin was in good linearity with the range of 2.4 μg/mL-12.0 μg/mL with the regression equation A=0.088C＋0.09,r=0.999 9（n=5）.The average recovery rate was 99.74%,RSD=0.47%（n=5）.The results gotten by UV method were closed to those by HPLC.
出处
《动物医学进展》
CSCD
北大核心
2010年第3期68-70,共3页
Progress In Veterinary Medicine
关键词
盐酸沙拉沙星可溶性粉
含量测定
紫外分光光度法
sarafloxacin hydrochloride soluble powder
content determination
UV spectrophotometry
