摘要
酰氨基硫脲类化合物具有很好的生物活性，如消炎、抗菌、抗结核、抗癌、杀菌、杀虫及植物生长调节等，也是重要的有机合成中间体。因此，随着新型农药的开发研究，酰氨基硫脲类化合物又成为药物开发的热点之一。
Three nitrobenzoyl naphthalene aeyl thiosemicarbazides（ Ⅱa -Ⅱc）were synthesized by addition reaction of naphthalene acyl hydrazines with nitrophenyl isothiocyanates, which were obtained by the reaction of potassium thiocyanate with nitrobenzoyl chloride. The structures of the products were characterized by 1H NMR, IR and elemental analysis. The preliminary biological activity test indicated that the synthesized compounds could promote the growth of paddy root at the concentration of ling/L, the compounds of Ⅱa - Ⅱc had antibacterial activity against B. subtilis.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2010年第3期343-346,共4页
Chemical Research and Application
基金
河南省教育厅自然科学研究项目(200913150020)
南阳师范学院2006年专项资助项目(nytck009)
关键词
酰氨基硫脲
芳基酰肼
Α-萘乙酸
合成
生物活性
acylthiosemicarbazide
aroylhydrazine
α-naphthylacetic acid
synthesis
biological activity
