摘要
目的：研究人的初生时B_(19)感染状况及与母体的感染的相关关系。方法:采用巢式PCR法配对检测101对新生儿-产妇血中B19DNA。结果：①子体（新生儿）与母体（产妇）B19阳性3对（2．97％）、子体与母体均阴性71对（70．30％）、子体阳性母体阴性17对（16．83％），子体阴性母体阳性10对（9．90％）；②101对中103例新生儿（含两对双胞胎）B19检出率19．42％与产妇B19检出率12.87％比较差异无显著性，但显著高于本地区正常人群B19检出率8．72％（P＜0．01）；③20例B19阳性新生儿中2例为先天性脑积水与水肿儿。结论：新生儿及其母体产妇B19感染率较正常人群及著升高，产妇与新生儿B19检出率差异不大，B19母婴垂直传播与致畸作用有待进一步探讨。
Objective: In order to investigate the serum infection of human parvovirus B19 newborns and perinatalwomen.Metods:Sera of 101 pairs of newborn and perinatal woman were detected by nested polymerase chain reaction.Results: 13pairs of newborn and mother were positive of human parvovirus B19(2.97%).71 pairs were vegative(70.30%).2newborn positive,mother negative were 17 pairs(16.81%),viwborn negative ,mother positive were 10 pairs(9.90%).3positive rate of newborn was 19.42%,perinatal womnan was 12.87% both were higher than nomal people .Conclusion:Infection rate of human parvovirus B19 of newbom and perinatal woman is higher than nomal people.mother-newborn derect infection,perhaps connection.
出处
《广东医学》
CAS
CSCD
1998年第12期911-912,共2页
Guangdong Medical Journal
基金
广东省"五个一"科教兴医工程重点项目
关键词
细小病毒B19
母婴垂直传播
配对检测
Parvovirus B_(19) Mother-newborn derect infection Pair detection
