摘要
目的：观察胺碘酮治疗持续性室性心动过速（SVT）及心室颤动（VF）的临床疗效及安全性。方法：对利多卡因无效或电除颤不能维持的SVT及VF患者41例给予胺碘酮3~5 mg/kg静脉注射,随后以0.5~1.5 mg/min持续静脉泵入,同时口服胺碘酮200 mg,3次/d。如心律失常控制不佳,每隔20~30 min再注射75~150 mg,静脉用药平均1-3d,口服逐渐减量至维持量。结果：24 h胺碘酮静脉用量（1 126±168）mg,心律失常控制率24 h为65.9%、48 h为82.9%、72 h基本控制。14d后胺碘酮200-400 mg/d口服维持,随访3个月无复发。结论：胺碘酮静脉注射联合口服治疗SVT及VF安全有效。
Objective To observe the clinical effect and safety of amiodarone treating sustained ventricular tachycardia（SVT） and ventricular fibrillation（VF） by intravenous injection and oral medication.Method To give amiodarone 3~5 mg/kg by intravenous injection,then continue venous pumping at 0.5~1.5 mg/min,meanwhile oral administration amiodarone 200 mg,tid for 41 SVT and VF cases which were ineffective by lidocaine or untenable by electric defibrillation.If arrhythmia was not controlled well,amiodarone were reinjected 75~150 mg every 20~30 min,general for 1~3 d,then oral medication dose decreased progressively to the maintenance dose.Results Through intravenous injection amiodarone dose at（1 126±168） mg,arrhythmia control rate was 65.9% at 24 h,82.9% at 48 h,on the whole in control at 72 h.Follow-up visiting for 3 months,it had no recurrence by giving amiodarone 200~400 mg/d po after 14 d.Conclusion Treatment to SVT and VF by intravenous injection and oral medication of amiodarone is effective and safe.
出处
《吉林医学》
CAS
2010年第3期318-319,共2页
Jilin Medical Journal
关键词
胺碘酮
室性心动过速
心室颤动
Amiodarone
Sustained ventricular tachycardia
Ventricular fibrillation
