摘要
目的建立气相色谱法测定消糜栓中冰片（以龙脑计）的含量。方法采用气相色谱法，色谱柱为聚乙二醇-20M毛细管柱30m×0．53mm×0．25μm，程序升温，起始温度90℃，每分钟升10℃，升至170℃后保持10分钟，分流比50：1，FID检测器；检测口温度为250℃。结果用气相色谱法测定消糜栓中冰片（以龙脑计）在0．127～0．762g·L^-1范围内呈良好的线性关系，线性方程为Y=0．7339—0．4077X，r=0．9998。平均回收率98．3％（n=9），RSD1．4％。结论本方法简便、准确、快速，可用于消糜栓的质量控制。
Aim To establish a gas chromatography （GC） method to determine the content of borneol in xiaomi suppository. Method A PEG-20M column was used （30m×0.53mm×0.25μm）. Column temperature was raised by programming,with an original temperature at 90℃ ,then raised to 200℃ at the rate of 10℃· min^-1 and kept for 10 minutes. Distributary ratio was 50：1 and FID temperature was 250℃. Results The linear range of borneol was from 0.127 to 0. 762 g · L^- 1. The average recovery was 98.3 % （ n = 9） , and RSD was 1.4 %. Conclusion The method is simple, accurate and quick,which can be used to control the quality of xiaomi suppository.
出处
《安徽医药》
CAS
2010年第4期415-416,共2页
Anhui Medical and Pharmaceutical Journal
