摘要
作者采用噻唑蓝(MTT)法对36例恶性肿瘤合并恶性腹水患者腹水肿瘤细胞进行化疗药物敏感性测定,并根据测定结果进行临床化疗,结果表明,腹水可用于药物敏感性测定,可评价率为75%;腹水标本可替代实体瘤标本作体外化疗药物敏感试验;不同肿瘤患者个体之间药物敏感性不同;药敏结果用于个体化治疗效果良好。
36 cases of malignant ascites undergo chemotherapy depending on MTT assay for drug sensitivity of their fluid tumor cell.The result showed that the ascites sould be used in drug senstivity detection and coincident rate is 75%,ascitic specimen can be used in drug sensitivity detection in vitro instead of solid tumor.The sensitivities of different patients are different.
关键词
MTT
腹水
药敏试验
药物疗法
MTT assay Malignant ascites Drug sensitivity chemotherapy