摘要
目的分析糖化血红蛋白（HbA1c）对筛查妊娠糖尿病（GDM）的应用意义。方法对98例正常妊娠组、52例糖耐量异常组和79例GDM组进行了空腹血糖（FPG）口服葡萄糖50g筛选测定（GCT）及糖化血红蛋白（HbA1c）测定。结果GDM组FPG、GCT、HbA1c较正常妊娠组均显著增高（P〈0．05）。正常妊娠组与糖耐量异常组FPG、GCT阳性率基本一致，两组比较无统计学意义（P〉0．05）。而糖耐量异常组HbA1c阳性率明显高于正常妊娠组，两组差异统计学意义（P〈0．05）。结论测定糖化血红蛋白（HbAk）方法快速、简便、实用，取血量少，可作为GDM诊断筛查的指标。
Objective To analyze the glycosylated hemoglobin （HbAlc） to the screening of gestational diabetes mellitus （GUM） the application of the meaning. Methods 98 patients with normal pregnancy group, 52 patients with abnormal glucose tolerance group and 79 cases of GDM group had fasting plasma glucose （FPG）, oral administration of 50g glucose screening measurement （GCT） and glycosylated hemoglobin （HbAlc） measurement. Results GDM group FPG, GCT, HbAlc compared with the normal pregnancy group were significantly higher （P 〈0.05）. Normal pregnancy group and impaired glucose tolerance group of FPG, GCT-positive rate of basically the same, the two groups was not statistically significant （P〉 0.05）. The positive rate of impaired glucose tolerance group HbAlc was significantly higher than the normal pregnancy group, statistically significant differenee between the two groups （P 〈0.05）. Conclusion The determination of glycated hemoglobin （HbAlc） method is rapid, simple, practical, take less blood can be used as diagnosis of GDM screening indicators.
作者
杨良妹
YANG Liang-mei （Huizhou Liang-mei and Children Health Centre,Huizhou 516001,China）
出处
《医学信息》
2010年第4期945-947,共3页
Journal of Medical Information
