摘要
为探讨缺血性脑血管病的复发情况及其危险因素,采用以医院为基础的队列研究,对近5年缺血性脑血管病住院病人774例进行随访调查.发现其1年、3年及5年的累积复发率分别为5.9%、10.3%及14.5%。经 COX 比例风险模型单因素及多因素分析显示:糖尿病史、家族卒中史、病后未服阿司匹林及血压控制不佳是影响复发的独立危险因素,相对风险度分别为3.16、1.55、2.38及1.59。提示在缺血性脑卒中二级预防工作中,可将糖尿病史及家族卒中史作为识别高危复发人群的重要标志,病后长期服用阿司匹林及规律服用降压药是预防复发有效的干预措施。
A hospital-based cohort study was conducted to investigate the recurrent condi- tions and risk factors of ischemic stroke.774 in-patients of ischemic stroke during 1991～1996 were followed up.The results showed that 112 cases were recurrent,one、three and five years cu- mulative recurrent rates were 5.9%,10.3% and 14.5% respectively.By Cox proportional hazards analysis it was found that there were four independent risk factors of ischemic stroke:history of di- abetes mellitus(RR:3.16,P<0.001)、family stroke history(RR:1.55,P<0.05)、history of tak- ing aspirin after primary stroke(RR:2.38,P<0.001)and poor control of blood pressure after first stroke(RR:1.59,P<0.001). In conclusion,history of diabetes mellitus and family stroke history were important marks to recognize high risk recurrent cohort in secondary prevention of ischemic stroke.After primary stroke,long-term taking aspirin and taking hypotensor regularlt were effective preventive measures of recurrent stroke.
出处
《卒中与神经疾病》
1998年第4期192-195,共4页
Stroke and Nervous Diseases
关键词
缺血性脑血管病
复发
危险因素
回归分析
Ischemic cerebrovascular disease
Recurrence
Risk factors
Regression analysis
