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乳化碘油增强CT对大鼠肝脏病变诊断价值初步评价

Experimental Study of Intravenous Hepatosplenography With a New Iodized Oily Emulsion for Detection of Small Liver Foci:Preliminary Results
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摘要 目的:初步评价乳化碘油增强CT对大鼠肝脏炎性假瘤的诊断作用。材料与方法:将甘油、卵磷脂及超液化碘油乳化成油包水乳剂;按0.422g碘/kg剂量,静脉注入10只大鼠肝炎性假瘤模型,CT观察瘤灶的显示情况。结果:正常肝脏均匀一致高度强化,清楚显示出低密度瘤灶。结论:乳化碘油是一种有潜在价值的肝脾高度特异性造影剂,对肝脏小病灶显示有重要作用。 Purpose: To prelitninarily evaluate the roles of iodized oily emulsion enhanced CT for detecting inflammatory pseudotumor of the liver (IPL ). Materials and Methods: lodized oily emulsion were prepared by sonificated the mixing of glycerol,lecithin and lipiodol ultra-fluid. 10 SD rats with IPL were established by local injection of Freund's complete adjuvant. All the rat models wete underwent CT scans belore and 1 hour after administration of iodinated oily emulsion at a dose of 0. 422gI/kg-.Results: The CT densities of normal parenchymas of the livers were consisderably increased, while the attenuations of IPL le-sions remained hypodense. Therefore, the liver/lesion contrast difference were well improved. Couclusion: our initial results indi-cated that iodinated oily emulsion is a potential hepatosplenic-seeking conttast agent. It might play an important role in detecting tiny hepatic foci.
出处 《现代医用影像学》 1998年第6期272-273,共2页 Modern Medical Imageology
关键词 碘油 乳剂 肝脏病变 诊断 CT Liver Spleen Computed Tomography Iodinated Oil Emulsion
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