摘要
目的观察癌抗原125(CA125)、癌抗原153(CA153)、癌抗原72-4(CA72-4)对卵巢癌的诊断及疗效观察的价值。方法采用电发光法检测32例卵巢癌和21例妇科良性疾病患者血清中CA125、CA153和CA72-4水平。结果卵巢癌患者血清中CA125、CA153和CA72-4含量高于良性对照组,联合检测CA125和CA72-4特异性、敏感性优于单独检测及其它组合。卵巢癌患者治疗后CA125、CA153和CA72-4降低(P<0.05～0.01)。结论联合检测CA125和CA72-4对卵巢癌的诊断有重要的临床价值,弥补了单独检测CA125的不足。
Objective To explore the significance of serum CA125, CA153 and CA72 - 4 in diagnosis and therapeutic response of ovarian carcinoma. Methods Serum levels of CA125, CA153 and CA724 were detected by electrochemical method. Results Serum levels of CA125, CA153 and CA72 -4 were notably increased in patients with ovarian carcinoma in comparison with those of benign controls （ P 〈0.01 ）. The specificity and sensitivity of combined examination of serum CA125 and CA72 -4 were much better than individual detection and other combinations. The serum levels of CA125, CA153 and CA72 -4 in patients with ovarian carcinoma were notably decreased after treatment （ P 〈0.01 ）. Conclusion The clinical significance of combined detection of serum levels of CA125 and CA72 -4 is important in diagnosis of ovarian carcinoma, and it can make up the deficiency of individual detection of CA125.
出处
《临床和实验医学杂志》
2010年第8期568-569,共2页
Journal of Clinical and Experimental Medicine
