摘要
目的:研究益肾蠲痹法治疗系统性红斑狼疮的疗效。方法:本研究应用"益肾蠲痹法"对54例曾用激素或免疫抑制剂治疗系统性红斑狼疮,因副作用而改用益肾蠲痹法治疗3年以上的患者,观察治疗前后临床疗效、症状积分、激素剂量、血沉、C反应蛋白、ENA系列等指标变化。结果:54例系统性红斑狼疮患者治疗后的症状积分显著下降,ESR、CRP明显下降;激素用量逐渐撤减至停服,ENA系列指标阴转率最高达96.3%。结论:益肾蠲痹法对难治性系统性红斑狼疮,具有疗效高、毒副作用小、症状及实验室指标改善明显等理想疗效,是一种易于推广使用、具有良好产业化前景的治疗方法。
The effect of Yi Shen Juan Bi Fa （reinforcing kidney expelling impediment method） on systemic lupus erythematosus treatment was studied in this work. In this retrospective study, 54 patients who had given up the therapy of glucocorticoid or immunosuppressants because of the side effects and then chosen the treatment of Yi Shen Juan Bi Fa for 3 years were selected to observe the clinical efficacy before and after the treatment. The indicators included the changes of symptom scores, glucocorticoid dosage, erythrocyte sedimentation rate, CRP, ENA series, etc. All 54 patients were observed to have significantly decreased symptom scores, ESR and CRP after the treatment. The glucocorticoid dosage was gradually reduced to be withdrawn and finally to be stopped. The negative rate of the indicators of the ENA series reached up to 96.3%. The results showed that Yi Shen Juan Bi Fa has potential in treating refractory systemic lupus erythematosus, with high efficacy, low toxic side effects, significantly improved symptoms and laboratory indicators. This method is easy for promotion, thus may have good prospects for the commercialization.
出处
《世界科学技术-中医药现代化》
2010年第1期71-75,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家中医药管理局2005年全国中医药科技成果推广项目[国中医药办发(2005)30号]:益肾蠲痹法治疗风湿病
负责人:朱婉华
关键词
益肾蠲痹法
系统性红斑狼疮
虫类药
不良反应
Yi Shen Juan Bi Fa （reinforcing kidney expelling impediment method）
Systemic lupus erythematosus
Side effects
