摘要
泰妙菌素(Tiamulin)又称泰妙灵、支原净、泰牧霉素,是由高等真菌担子菌侧耳属Pleurotusmutilus和Pleurotuspasseckerianuus菌种的深层培养液提取的截短侧耳素(Pleuromutilin)的氢化延胡索酸盐,是双萜烯化合物半合成的抗生素。泰妙菌素在动物体内吸收迅速,血药浓度高,体内分布广泛,且残留较低,对革兰氏阳性菌(如金黄色葡萄球菌、链球菌)、支原体(猪肺炎支原体、鸡败血支原体)、猪胸膜肺炎放线杆菌和猪蛇形螺旋体等有较强的抗菌活性,对支原体和蛇形螺旋体尤为敏感。
同被引文献27
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