摘要
目的探讨嗜酸粒细胞性胃肠炎（eosinophilic gastroenteritis,EG）临床表现、内镜、病理特点及诊治方法。方法回顾性分析我院2003年1月～2008年9月的27例住院EG患者的临床资料,对其临床分型及诊治方法进行分析。结果本组27例EG中黏膜型17例、浆膜型4例、黏膜浆膜混合型5例及黏膜肌层混合型1例。85.19%的患者以腹痛为首发症状,内镜检查病变多分布在胃窦、十二指肠降部和回盲部。活体组织病理学检查或腹水细胞学发现大量嗜酸粒细胞浸润。予以糖皮质激素或抗组胺类药物,腹痛症状均在1周内缓解。结论EG主要发生于20～50岁青中年患者,以黏膜型最常见,多以腹痛为主要症状且常规镇痛药物疗效不佳,内镜活体组织病理学检查或腹水细胞学检查有助于明确诊断。糖皮质激素治疗疗效显著。
Objective To investigate the clinical,endoscopic and pathological characteristics,diagnosis and therapy of eosinophilic gastroenteritis（EG）.Methods The clinical data of 27 patients with EG in our hospital from January 2003 to September 2008 were analyzed retrospectively in clinical types,diagnosis and treatment.Results There were 17 mucosal EG,4 serosal EG and 6 combination EG.The major clinic sign of 85.19% patients was abdominal pain.The lesions in endoscopy were mostly located at antrum,descending part of duodenum and ileocecal junction.A lot of eosinophilic cells were found by biopsy under endoscope or cytological examination of ascites.The abdominal pain could be relieved in a week after treatment with steroid or antihistamines.Conclusion EG mainly occurs in youth aged 20~50 years old.The most common type is mucosal type of EG.Abdominal pain can not be treated by conventional analgesics.Biopsy under endoscopy or cytological examination of ascites is necessary to the diagnosis.Patients with EG well respond to therapy with steroid.
出处
《胃肠病学和肝病学杂志》
CAS
2010年第3期258-260,共3页
Chinese Journal of Gastroenterology and Hepatology
关键词
嗜酸粒细胞性胃肠炎
腹痛
内镜
Eosinophilic gastroenteritis Abdominal pain Endoscopy
