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左炔诺孕酮宫内缓释系统治疗围绝经期功血的疗效观察 被引量:10

Effectiveness of Levonorgestrel Intrauterine System in Treating Dysfunctional Uterine Bleeding During Peri-menopausal Period
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摘要 目的:观察左炔诺孕酮宫内缓释系统((levonorgestrel intrauterine system,LNG-IUS,商品名:曼月乐)对围绝经期功能失调性子宫出血(围绝经期功血)的临床疗效。方法:对39例子宫内膜诊刮诊断为功能失调性子宫出血患者放置曼月乐,在放置前和放置后12个月内定期B超监测子宫内膜厚度,观察患者血红蛋白情况及月经改善情况。结果:置宫内节育器3个月后,子宫内膜厚度由(12.5±6.3)mm降至(7.5±2.3)mm,血红蛋白由(88.46±11.3)g/L上升至(115.4±7.5)g/L,月经量明显减少,由置宫内节育器前(164.9+41.5)ml降至(52.2±13.8)ml,置宫内节育器前后两者比较差异具有统计学意义。结论:曼月乐治疗围绝经期功能失调性子宫出血疗效好,值得临床推广。 Objective:To observe the clinical effectiveness of Levonorgestrel intrauterine system (Mirena) in treating dysfunctional uterine bleeding during peri-menopausal period.Methods:39 patients,diagnosed with dysfunctional uterine bleeding by dilation and curettage,were placed with Mirenas.The haemoglobin and menstruati Dn of these patients were observed and the endometrium width was examined via B ultrasound both before and after the placement.Results:3 tnonths later after the placement of the devices,the haemoglobin of these patients was increased from (88.46±1.33 to (115.4±7.5)g/L with significant decrease of the menstrual volume from (164.9±41,5) to (52.2 ±13.8) ml and the reduction of the endometrium width from (12.5±6.3)to (7.5±2.3) mm.Conelusion:Mirena is worthy of wide utilization in clinic due to its good effectiveness in treating dysfunctional uterine bleeding during peri-menopausal period.
作者 余韬 张云霞
出处 《中国医药导刊》 2010年第3期445-445,449,共2页 Chinese Journal of Medicinal Guide
关键词 左炔诺孕酮宫内缓释系统 围绝经期功能失调性子富出血 治疗效果 Levonorgestrel intrauterine system Dysfunctional uterine bleeding during peri-menopausal period Clinical effectiveness
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参考文献4

  • 1刘冬娥.女性围绝经期的生理和病理变化[J].中国实用妇科与产科杂志,2004,20(8):473-474. 被引量:248
  • 2Jondet M,Letellier B,Verdys M T.Endometrial Vascularization in Levonorgestrel Intrauterine Device Uers:Computerized Microvessel measurement study[J]. Contraception,2005; 71 ( 1 ):60-64.
  • 3Roopa B A,Loganath A,Singh K.The Effect of a Levonorgestrel-releasing Intrauterine System on Angiogenic Growth Factors in the Endometrium[J].Hum Reprod,2003; 18(9): 1809-1819.
  • 4Oliveira Ribeiro M.Petta C A,Andrade L A.Correlation between Endometrial Histology, Microvascular Density and Cablre,Matrix Metalloproteinase-3 and Bleeding Pattern in Women using a Levonorgestrel-releasing Intrauterine System[J].Hum Reprod,2004; 19(8): 1778-1784.

二级参考文献5

  • 1Prior JC.Perimenopause:the complex endocrinology of the menopausal transition.Endocrinol Rev,1998,19:397
  • 2Faddy MJ,Gosden RG,Gougeon A,et al.Accelerated disapperance of ovarian follicles in mid-life:implications for forecasting menopause.Hum Reprod,1992,7:1342
  • 3Bruschi F,Meschia M,Soma M,et al.Lipoprotein and other lipids after oophorectomy and estrogen replacement therapy.Obstet Gynecol,1996,88:950
  • 4郭成秀.女性骨质疏松相关因素和测定方法[J].国外医学(妇产科学分册),1999,26(2):74-77. 被引量:5
  • 5张以文,陈蔚林,郁琦,宋耀红,周京,张德永.绝经过渡期妇女血清抑制素水平的研究[J].中华妇产科杂志,2003,38(2):98-101. 被引量:22

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