摘要
细胞核相关抗原(Nuclear-associated antigen)Ki67属于IgG1家族,为非组蛋白,对蛋白酶高度敏感。是由两条相对分子量为345 ku和395 ku的多肽链组成的大分子蛋白质,位于细胞核内,与细胞分裂密切相关。作为一种核增值抗原,Ki67被大量用于各种肿瘤相关性疾病的研究中,下面我们就其在肺癌中的表达及其相关研究综述如下。
The nuclear-associated antigen Ki67,Ki67 belong to IgG1 family,non-histone proteins,is highly sensitive to the protease.By the two molecular weight 345ku and 395ku peptide chains of protein molecules,located inside the nucleus,and cell division are closely linked.As a core value-added antigen,Ki67 has been widely used for various cancer-related diseases research,the following we on its expression in lung cancer research are summarized below.
出处
《内蒙古医学杂志》
2010年第2期213-214,共2页
Inner Mongolia Medical Journal
