摘要
目的探讨依达拉奉对急性脑梗死治疗的临床疗效。方法将130例急性脑梗死患者分为依达拉奉治疗组和对照组（常规治疗）,每组65例,两组均给予血小板聚集抑制剂、改善微循环药物和神经营养药物等基础治疗;将两组患者治疗前后神经功能缺损评分（NIHSS）之差和血液动力学指标进行对比分析。结果治疗前与治疗后神经功能缺损评分之差两组有显著差异（P〈0.05）,血流动力学指标无统计学差异（P〉0.05）。结论在脑梗死急性期依达拉奉对缺血大脑组织具有保护作用,对血流动力学无明显影响,合并出血的风险小。
Objective To research clinical efficacy of edaravone in treatment on acute cerebral infarction.Methods One hundred and thirty cases with acute cerebral infarction were divided into edaravone treatment group（n=65）and control group（n=65,accepting conventional treatment）.Two groups were given platelet aggregation inhibitors,and basic drugs therapy including drugs of improving microcirculation and neurotrophic drugs.Deference in neurological deficit score（NIHSS） of the two groups and hemodynamic indexes were analyzed.Results There was significant difference in neurological deficit score（NIHSS） between the two groups（P〈0.05）,while the hemodynamic indexes was of no statistical difference before and after treatment（P〉0.05）.Conclusions Edaravone has protection effect on ischemia brain of patients with acute cerebral infarction,and no obvious influence on hemodynamics with little risk of combining with hemorrhage.
出处
《地方病通报》
2010年第1期87-88,共2页
Endemic Diseases Bulletin
关键词
脑梗死
自由基清除剂
依达拉奉
治疗
Cerebral infarction Radical scavenger Edaravone Treatment
