摘要
目的:通过对人工合成材料重建膝交叉韧带研究进展的研究和临床实验观察,着重探讨其重建后在损伤修复中的应用前景。方法:由第一作者应用计算机检索维普数据库与人工合成材料重建膝交叉韧带有关的文献,检索时限为1993-01/2009-10。检索关键词:膝关节交叉韧带;人工韧带;移植重建。纳入标准:①人工合成材料在膝交叉韧带损伤修复中应用等相关文献。②LARS人工韧带重建膝前、后交叉韧带的实验研究与临床应用相关的文章。排除标准:③排除较陈旧的理论观点以及一些重复性研究。对资料进行初审,并查看每篇文献后的引文。结果:计算机初检到105篇文献,阅读标题和摘要进行初筛,排除研究目的与本文无关的文献40篇,内容重复性研究44篇,共21篇文献符合标准。膝关节前交叉韧带断裂是一种严重的膝关节损伤,可导致膝关节不稳,并可继发关节内主要结构损伤,严重影响关节功能。对于要求锻炼的年轻患者,特别是运动员前交叉韧带损伤,LARS人工韧带是理想移植材料。目前为止,LARS人工韧带的并发症报道比例较小,特别是没有滑膜炎的报道,被认为是安全的移植材料。结论:人工韧带为前、后交叉韧带重建的确提供了一种选择,但仍存在不足之处,还不是最理想的移植物,也不能完全代替交叉韧带。
OBJECTIVE：To explore the prospect of artificial synthetic material in repairing knee cruciate ligaments injury by reviewing related study progress and clinical experiments.METHODS：Publications addressing artificial synthetic material in repairing knee cruciate ligaments injury in the VIP database between January 1993 and October 2009 were selected by computer.The research words including ＂knee cruciate ligaments,artificial ligaments,and reconstruction＂.Inclusion criteria：①Literatures relate to the application of artificial synthetic material in repairing knee cruciate ligaments injury.②Papers addressing reconstructing anterior,posterior cruciate ligaments by using LARS artificial ligaments.Exclusion criteria：obsolete theoretical views and repetitive studies.The data were checked in the first trial,and the quotations were reviewed.RESULTS：In total,105 literatures were initial searched by computer,40 unrelated and 44 repetitive studies were excluded after screening.Therefore,21 literatures were included in this paper.The cruciate ligament rupture is a severe knee joint injury,which can lead to knee joint instability,damage intra-articular structures,and seriously affect the joint function.LARS artificial ligament is preferred candidate for young patients,especially for athletes with anterior cruciate ligament.LARS artificial ligament is considered to be a safe transplant material because that few reports concerning its complication,particularly,no synovitis was reported following LARS artificial ligaments implantation.CONCLUSION：LARS artificial ligament provides a selection for anterior,posterior cruciate ligaments reconstruction.However,it is can not substitute cruciate ligament completely due to its limitation.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2010年第8期1451-1454,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
