摘要
以DMSO为溶剂，碳酸二乙酯为酰化试剂，4-取代-2-羟基苯乙酮在氢化钠的催化下，经一步反应合成了7个新型的7-取代4-羟基香豆素，产率49％-90％，其结构经1^H NMR表征。
4-Hydroxyl coumarin and seven novel 7-substituted-4-hydroxyl coumarins in yields of 49% - 90% were synthesized from 4-substituted-2-hydroxyl acetylbenzene by a one-step reaction using DMSO as the solvent, diethyl carbonate as the acidylating agent, and sodium hydride as the catalyst. The structures were characterized by 1^H NMR.
出处
《合成化学》
CAS
CSCD
北大核心
2010年第2期232-234,共3页
Chinese Journal of Synthetic Chemistry
基金
四川省教育厅青年基金资助项目(2006B020)
关键词
4-羟基香豆素
合成
4-hydroxyl coumarin
derivative
synthesis
