摘要
目的探讨氩离子凝固术(APC)在消化道病变内镜介入治疗中的临床应用。方法2005年3月～2009年3月,采用内镜下APC单独或联合治疗509例消化道病变患者,并观察其治疗效果。结果353例胃肠道广基、扁平息肉及息肉残迹经APC治疗后3个月内复查内镜,黏膜色泽正常,原治疗部位无复发。68例成熟型疣状胃炎患者治疗后1月临床症状明显改善,内镜复查病灶好转或消失。17例Barrett食管患者6个月后内镜及病理检查示14例恢复为鳞状上皮,12个月后复查未见复发。38例消化道出血经APC治疗后均未再出血。12例食管支架植入术后再狭窄晚期食管癌患者经APC治疗后实现再通。15例食管中重度不典型增生患者经APC治疗病灶消除。6例联合黏膜切除术早期癌患者治愈。均无严重并发症。结论APC在消化道病变内镜介入治疗中效果显著,且简便易行,并发症少,有较高的临床应用价值。
Objective To investigate the clinical application of argon plasma coagulation in ineerventional endoscopic treatment of digestive diseases.Methods 509 patients suffering from digestive diseases were treated by interventional endoscopic treatment with the aid of APC from Mar 2005 to Mar 2009,and the effect of the treatment was obserevd.Results For 353 cases of gastrointestinal polyp and polyp remnants,the lesions were eliminated,which were confirmed by endoscopy 3 months after APC treatment,and the color of mucosa was normal and no recurrence in the place where the polyps were treated.For 68 cases with mature verrucosa gastritis,the lesions were improved or disappeared and the clinical symptoms were improved obviously when examed by endoscopy 1 month later.For the 38 cases with digestive tract hemorrhage,no hemorrhage was found after APC treatment.In the 17 cases with Barrett＇s esophageal who were treated with APC,squamous cell epithelium was found to recovered as shown by endoscopy and biopsy 6 months after the treatment,and no recurrence 12 months later for 14 cases.For the 12 cases of advanced stage of esophageal carcinoma with esophageal stent implantation,restenosis became recanalize after APC treatment.For the 15 cases of with middle severe esophageal dysplasia,the lesions were disappeared after APC treatment.6 cases with early carcinoma were cured with EMR and APC.No severe complications happened in all cases.Conclusion APC is an effective method in the interventional theraputic endoscopy in digestive system diseases,and APC can be widely used in clinic for its convenience and rare complication.
出处
《临床消化病杂志》
2010年第1期10-12,共3页
Chinese Journal of Clinical Gastroenterology
关键词
氩离子凝固术
消化道病变
内镜介入治疗
Argon plasma coagulation
Digestive system diseases
Interventional therapeutic endoscopy
