摘要
在Ｃｙ诱导的免疫功能增高和降低模型上，分别观察了Ｓｅｙ对ＤＴＨ的影响。结果发现，在免疫功能增高状态下，Ｓｅｙ能不同程度的抑制ＤＴＨ（６０、９０ｍｇ／Ｋｇ剂量组）、Ｃｙ导致的脾（６０ｍｇ／Ｋｇ剂量组）及胸腺重量的增加；在Ｃｙ诱导的免疫功能低下状态下，三个剂量的Ｓｅｙ均对Ｃｙ抑制的小鼠ＤＴＨ有拮抗作用，并能部分对抗Ｃｙ所制的胸腺及脾指数的降低。提示，Ｓｅｙ在不同的免疫状态下对淋巴细胞的功能有双向调节作用。
Effects of selenium-enriched yeast on the DTH in the mouse with the enhanced and suppressed immune function were investigated.It was found that Sey could inhibit the increase of DTH,thymus,and spleen in the mouse with enhanced immune function induced by cyclophosphamide at different doses.Meanwhile,Sey could enhanced DTH and increased the weight of thymus and spleen in suppressed immmune mouse.IT suggests that Sey may regulate the lymphocytes functions in different immune state.
出处
《微量元素与健康研究》
CAS
1998年第4期7-8,共2页
Studies of Trace Elements and Health
关键词
富硒酵母
迟发型
变态反应病
DTH
Selenium-enriched yeast Spleen Thymus Delayed-type hypersensitivity(DTH)
