摘要
脓毒症心功能障碍是脓毒症多器官功能障碍的表现之一。脓毒症心功能障碍的临床和基础研究已超过50年，但其具体病理生理机制还不完全明确。现阶段的研究认为：线粒体功能障碍、循环中各种心肌抑制物、心肌细胞内钙稳态失调等共同作用促进了脓毒症时心功能障碍的发生。
Myocardial dysfunction is a well-recognized manifestation of multiple organ dysfunction in sepsis. Although the underlying mechanisms of myocardial dysfunction during sepsis have been studied for more than 5 decades, the detailed pathophysiology of sepsis-induced myocardial dysfunction still remains unclear. The underlying mechanisms of myocardial dysfunction include mitochondrial dysfunction, circulating myocardial depressant factor, impaired calcium balance and etc.
出处
《中国小儿急救医学》
CAS
2010年第2期169-171,共3页
Chinese Pediatric Emergency Medicine
关键词
脓毒症
心功能障碍
机制
Sepsis
Cardiac dysfunction
Mechanism
