摘要
痤疮的发病机制较为复杂。研究表明，痤疮丙酸杆菌与痤疮的发生有重要的关系，在多个致病因素中起核心作用，然而痤疮丙酸杆菌在痤疮中的作用尚不完全清楚。随着医学研究的不断发展，痤疮丙酸杆菌基因功能的破解、痤疮丙酸杆菌生物膜致病耐药机制的不断完善、痤疮丙酸杆菌表面唾液酸酶为靶位的疫苗研发等为了解痤疮丙酸杆菌的致病机制和治疗提供线索。
Acne has a complex pathogenesis. It has been shown that P. acnes plays a key role at various levels in the pathogenesis of acne, however, the exact contribution of P. aches remains unknown. With the progress of medical research, the decipherment of gene functions, deep understanding of resistance mechanism and development of vaccines targeting surface sialidase of P. aches will offer clues to the exploration into pathogenic mechanisms of P. aches and acne treatment.
出处
《国际皮肤性病学杂志》
2010年第2期86-88,共3页
International Journal of Dermatology and Venereology
关键词
痤疮
寻常
痤疮丙酸杆菌
疫苗
Acne, vulgaris
Propionibacterium acnes
Vaccines
