摘要
肝细胞癌是世界上最常见的恶性肿瘤之一,对肝癌的早期诊断,亦即小肝癌(SHCC)的诊断并及时治疗是延长肝癌患者生存期的关键.近年来随着各种影像学技术的不断进步,SHCC的检出率在逐年增高.对众多不适合或不愿手术治疗的部分患者而言,SHCC检出率提高不仅意味着可以避免不必要的外科手术,并且可得到早期治疗,提高患者的生存率和预后,极大减轻患者的身心负担.目前以射频消融(RFCA)、微波消融、经皮肝穿瘤内无水乙醇注射及超选择性插管与节段性栓塞(S-TACE)等为代表的介入疗法在SHCC治疗上已经取得了较好的疗效.尤其是射频消融疗法的5年生存率达58.22%,与手术(55.51%)组无差别,使之成为当前和今后SHCC非手术治疗的主要方法.因此,及时准确地对SHCC患者做出诊断,不仅可以减轻患者的痛苦,同时也可延长患者的生存期.本文对国内外有关SHCC的各种影像学诊断进展作一综述如下,以期提高临床医生对SHCC的认识,为SHCC的早期诊断和治疗作出一定贡献.
Hepatocellular carcinoma （HCC） is one of the most common malignant tumors worldwide.Early diagnosis and treatment of small hepatocellular carcinoma （SHCC） are key to improvement of the survival of HCC patients.The advances in imaging technology have led to an increase in the detection rate of SHCC.For patients who are not suitable for surgical treatment,early detection of SHCC can not only help avoid unnecessary operation and improve survival and prognosis but also help alleviate the patient＇s physical and mental burden.Nowadays,intervention therapies,such as radiofrequency catheter ablation （RFCA）,percutaneous ethanol injection,and superselective transcatheter arterial chemoembolization （S-TACE）,show satisfactory efficacy in the treatment of SHCC.As the five-year survival rate achieved after RFCA （58.22%） is comparable to that after surgery （55.51%）,RFCA has become a primary non-surgical therapy for SHCC.In this article,we will review the recent advances in imaging diagnosis of SHCC.
出处
《世界华人消化杂志》
CAS
北大核心
2010年第5期479-486,共8页
World Chinese Journal of Digestology
关键词
肝细胞癌
小肝癌
超声
超声造影
X线计算机体层摄影
核磁共振成像
数字减影血管造影
Hepatocellular carcinoma
Small hepatocellular carcinoma
Ultrasound
Contrastenhanced ultrasonography
X-ray computed tomography
Magnetic resonance imaging
Digital subtraction angiography
