摘要
目的:探讨支气管肺炎患儿治疗前后血清hs-CRP、TNF-α和M-CSF水平的变化及意义。方法:应用放免法和免疫比浊法对36例支气管肺炎患儿进行了治疗前后血清hs-CRP、TNF-α和M-CSF水平检测,并与35名正常健康儿作比较。结果:支气管肺炎患儿在治疗前血清hs-CRP、TNF-α和M-CSF水平均非常显著地高于正常儿组(P<0.01),经系统治疗2周后则与正常儿组比较无显著性差异(P>0.05)。结论:检测支气管肺炎患儿血清hs-CRP、TNF-α和M-CSF水平的变化对探讨其发病机理、预防和指导用药均有重要的价值。
Objective To study the significance of changes of serum hs-CRP,TNF-α and M-CSF levels after treatment in pediatric patients with bronchopneumonia. Methods Serum TNF-α,M-CSF （with RIA） and hs-CRP （with immunoturbidimetry） levels were determined in 36 pediatric patients with bronchopneumonia both befor and after treatment as well as in 35 controls. Results Before treatment,the serum hs-CRP,TNF-α and M-CSF levels were significantly higher in the patients than those in controls（P0.01）. After treatment for 2 weeks,the levels in patients were not much different from those in controls（P0.05）. Conclusion Detection of serum hs-CRP,TNF-α and M-CSF levels might reflect the progress of diseases in pediatric patients with bronchopneumonia.
出处
《放射免疫学杂志》
CAS
2010年第2期138-139,共2页
Journal of Radioimmanology
关键词
支气管肺炎
超敏C-反应蛋白
肿瘤坏死因子-α
巨噬细胞集落刺激因子
bronchopneumonia
high-sensitive-C reactive protein （hs-CRP）
tumor necrosis factor-α（TNF-α）
macrophage colony-stimulating factor （M-CSF）
