摘要
目的：应用减寿年数（ＰＹＬＬ）和减寿率（ＰＹＬＬＲ）计算指标评价分析晚期血吸虫病（晚血）患者死因对血吸虫病已完全控制地区人群寿命的影响。方法：对上海市郊经历年随访的３个原重流行乡于１９５５－１９９５年发生的晚血死亡患者４８７例的死亡原因按ＰＹＬＬ计算公式，分析其总ＰＹＬＬ、ＰＹＬＬＲ、各种死亡原因的ＰＹＬＬＲ及逐年的演变。结果：３个乡晚血患者的全死因ＰＹＬＬＲ为２５６．３‰，主要死亡原因为肝功能衰竭（１００．３‰）、肝癌（４３．４‰）和其他器官恶性肿瘤（２４．８‰），其中晚血并发肝功能衰竭和上消化道出血的ＰＹＬＬＲ，６０年代分别为２２２．２‰和３４．５‰，肝硬化并发症的ＰＹＬＬＲ占总ＰＹＬＬＲ的６７．５％。未切脾组明显高于切脾组。血吸虫病控制后，全死因及晚血并发症死因的ＰＹＬＬＲ均呈线性下降，９０年代全死因和晚血并发症死因的ＰＹＬＬＲ较６０年代分别下降６２．９％和８３．２％，上消化道出血的ＰＹＬＬＲ，近５年仅０．３‰。
AIM: To evaluate the effect of the causes of death of advanced schistosomiasis patients on the life span of population in an area where schistosomiasis had been under control by applying the indicators of potential years of life lost (PYLL) and rate of PYLL(PYLLR). METHODS: Using the formula of calculation of PYLL and PYLLR,the causes of death of 487 patients of advanced schistosomiasis in 3 previously endemic townships of Shanghai suburb . RESULTS: Of 487 cases who died between 1955 and 1995, the PYLLR of all causes of death was 256 3‰. The main causes of death were hepatic failure(100 3‰),liver carcinoma(43 4‰) and cancer of other organs (24 8‰). In the 1960s,the PYLLR of advanced schistosomiasis comlicated with hepatic failure and upper digestive tract hemorrhage was 222 2‰ and 34 5‰, the PYLLR of the complications of schistosomal liver cirrhosis, hepatic failure and hemorrhage accounted for 67 5% of the total PYLLR, being apparently higher in the non splenectomy group than in the splenctomty group . After the schistosomiasis was under control, both PYLL and PYLLR decreased linearly. As compared with the 1960s, the PYLLR of all causes of death and the causes of death of the complications of schistosomal liver cirrhosis in the 1990s has declined by 62 9% and 83 2%, respectively, the PYLLR of upper digestive tract hemorrhage was found only 0 3‰ in the last 5 years. CONCLUSION: PYLL and PYLLR analysis could be used to quantify the effect of complications of advanced schistosomiasis and other causes of death on the life span of population.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
1998年第6期449-453,共5页
Chinese Journal of Parasitology and Parasitic Diseases
关键词
减寿年数
减寿率
晚期
血吸虫病
Potential years of life lost(PYLL)
rate of PYLL
advanced schistosomiasis
