摘要
目的:分离鉴定连翘水提物中的化学成分。方法:采用薄层色谱、硅胶柱色谱、凝胶柱色谱和制备高效液相色谱进行分离纯化,通过理化方法和1H-NMR、13C-NMR等谱学技术进行结构鉴定。结果:分离得到8个化合物:硬脂酸(Ⅰ)、熊果酸(Ⅱ)、对羟基苯乙酸(Ⅲ)、3-(4-乙氧基-3-羟基-苯基)丙烯酸(Ⅳ)、异落叶松树脂醇(Ⅴ)、(+)表松脂素-4-O-β-D-葡萄糖苷(Ⅵ)、右旋表松脂素(Ⅶ)、右旋松脂素(Ⅷ)。结论:化合物Ⅲ为首次从该属植物中分离得到。
Objective：To study the chemical constituents of the extract with water from Forsythia suspensa. Methods： The compounds were isolated and repeatedly purified on TLC, silica gel column chromatograph, gel column chromatography, and preparative HPLC, and the structures were elucidated by physico-chemical properties and NMR. Results： Eight compounds were obtained and elucidated as stearic acid（Ⅰ）,ursolic acid（Ⅱ）,p-hydroxyphenyl acetic acid（Ⅲ）,3-（4-ehtoxoy-3-hydroxyphenyl）acrylic acid（Ⅳ）,isolariciresinol（Ⅴ）,epipinoresinol-4-O-β-D-glucoside（Ⅵ）,（＋）-epipinoresionl（Ⅶ）,（＋）-pinoresinol（Ⅷ）.Conclusion： Compound Ⅲ is isolated from this genus for the first time.
出处
《中药材》
CAS
CSCD
北大核心
2010年第2期220-221,共2页
Journal of Chinese Medicinal Materials
关键词
连翘
化学成分
结构鉴定
Forsythia suspensa（Thunb.）Vahl
Chemical constituents
Structure determination
