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单纯疱疹病毒感染状况分析 被引量:3

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摘要 目的探讨目前单纯疱疹病毒感染的临床特点及在疾病发生、发展过程中的作用。方法用单克隆抗体(McAb)酶联免疫吸附试验(ELISA)双抗体夹心法进行HSV型抗原检测。结果1009例妇女生殖器炎症标本,检出单纯疱疹病毒2型(HSV-2Ag)阳性标本268例,阳性检出率为26.58%;宫颈糜烂、淋病、滴虫性和霉菌性阴道炎HSV-2Ag阳性检出率分别为11.69%、5.45%、6.54%和2.88%。将宫颈糜烂程度分为3度进行检测,结果Ⅱ°和Ⅲ°的HSV-2Ag检出率分别是Ⅰ°的2.34倍和2.50倍。Ⅲ°宫颈糜烂所检出的21例HSV-2Ag阳性标本有1例为宫颈癌患者。结论提示上述疾病均可感染或混合感染HSV,HSV又可能是疾病发生和发展的原因之一;宫颈病变程度与HSV-2Ag阳性检出率正相关;HSV-2的感染与宫颈癌的发生关系密切。
出处 《齐齐哈尔医学院学报》 2010年第4期565-566,共2页 Journal of Qiqihar Medical University
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