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泌尿生殖道解脲脲支原体的药物敏感性分析 被引量:27

Drug Susceptibility of Ureaplasma urealyticum in Genitourinary Tract
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摘要 目的了解泌尿生殖道解脲脲支原体(Uu)感染状况及对抗菌药物的敏感性,为临床提供抗感染治疗的科学依据。方法回顾性调查2006年1月-2008年12月送检的泌尿生殖道分泌物标本解脲脲支原体培养的阳性结果。结果Uu检测总阳性率49.9%,其中女性阳性率60.5%,男性阳性率24.9%;Uu的耐药性特点为对喹诺酮类抗菌药物敏感率最低,对环丙沙星和氧氟沙星敏感率分别为15.0%和20.2%;对普那霉素、多西环素、交沙霉素、四环素敏感率最高,分别为99.8%、98.6%、92.8%、91.9%。结论Uu对常用抗菌药物已产生了不同程度的耐药性,泌尿生殖道Uu感染必须参照药敏试验结果,选用敏感率高的抗菌药物进行治疗。 OBJECTIVE To understand the infection status and drug sensitivity of Ureaplasma urealyticum(Uu) in the local region to provide the scientific accordance for the clinical anti-infective therapy.METHODS The positive culture of Uu from secretion in genitourinary tract from Jan 2006 to Dec 2008 was investigated retrospectively.RESULTS The total positive detection rate of Uu was 49.9%,60.5% for female and 24.9% for male.Uu in this region was characterized by the lowest drug sensitivity rate to quinolones.Drug sensitivity rate to ciprofloxacin and ofloxacin was 15.0% and 20.2%,respectively.And susceptibility to pristinamycin,doxycycline,josamycin,and tetracycline with the highest susceptibility was 99.8%,98.6%,92.8% and 91.9%,respectively.CONCLUSIONS Uu is resistant to commonly used antibiotics to varying degrees in the local region.The more susceptible antibiotics should be prescribed to treat genitourinary tract infection with Uu in reference to drug susceptibility testing.
作者 洪艳华
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2010年第8期1191-1192,共2页 Chinese Journal of Nosocomiology
关键词 解脲脲支原体 泌尿生殖道 感染 耐药性 Ureaplasma urealyticum Genitourinary tract Infection Drug-resistance
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