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原始神经外胚层肿瘤(PNET)1例光镜、免疫组化和电镜观察及文献复习 被引量:22

The histological, ultrastructural and immunohistochemical observation and review literatures of a case of primitive neuroectodermal tumor (PNET)
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摘要 目的:研究原始性神经外胚层肿瘤(PNET)的特征。方法:采用光镜、电镜和免疫组化对1例颈部原始性神经外胚层肿瘤(PNET)进行观察。结果:肿瘤组织由小圆形细胞构成,肿瘤细胞胞膜示MIC2强阳性,肿瘤细胞胞浆内含有微管及神经内分泌颗粒。结论:PNET是一种极度恶性的软组织小圆形细胞肿瘤,它的诊断必须依靠免疫组化及电镜。 Purpose To study the features of primitive neuroectodermal tumor. Methods A case of PNET was observed by light microscopy, electric microscopy and immunohistochemistry. Results PNET was composed of small round cells. Tumor cell membrane was positive for MIC2 antibody. Under electric microscopy, neuroendocrine granules and microtubules were noted in the tumor cell plasma. Conclusions PNET is a rare higly malignant soft tissue tumor. The diagnosis of PNET is established by immunohistochemical and ultrastructural studies.
出处 《临床与实验病理学杂志》 CAS CSCD 1998年第2期162-164,I025,共3页 Chinese Journal of Clinical and Experimental Pathology
关键词 原始性 神经外胚层肿瘤 电镜 免疫组织化学 primitive neuroectodermal tumor ultrastructure immunohistochemistry
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参考文献14

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